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Rani, M. Usha
- A Study on the Toxic Effects of Doxorubicin on the Histology of Certain Organs
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Source
Toxicology International (Formerly Indian Journal of Toxicology), Vol 19, No 3 (2012), Pagination: 241-244Abstract
In the present study, effect of doxorubicin at 2 mg/kg b.wt. (i/p), alone, once in a wk for 4 wks and in combination with vitamin E at 250 and 500 mg/kg b.wt., orally, daily for 4 wks was evaluated on histological alterations, if any, on heart, liver, kidney, and testes of rats. Doxorubicin alone treated group showed marked congestion and degenerative changes in heart, kidney, liver, and testis. Treatment with vitamin E showed marked improvement in all the degenerative changes, though more protection was observed with the dose of 500 mg/kg.Keywords
Doxorubicin, histopathology, vitamin-E Original Article on- Sero-biochemical Studies in Sheep Fed with Bt Cotton Plants
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Authors
B. Anilkumar
1,
A. Gopala Reddy
1,
B. Kalakumar
1,
M. Usha Rani
1,
Y. Anjaneyulu
2,
T. Raghunandan
3,
Y. Ramana Reddy
4,
K. Jyothi
1,
K. S. Gopi
1
Affiliations
1 Departments of Pharmacology and Toxicology, College of Veterinary Science, Hyderabad, Andhra Pradesh, IN
2 Veterinary Pathology, College of Veterinary Science, Hyderabad, Andhra Pradesh, IN
3 Livestock Research Institute, College of Veterinary Science, Hyderabad, Andhra Pradesh, IN
4 Department of Animal Nutrition, College of Veterinary Science, Hyderabad, Andhra Pradesh, IN
1 Departments of Pharmacology and Toxicology, College of Veterinary Science, Hyderabad, Andhra Pradesh, IN
2 Veterinary Pathology, College of Veterinary Science, Hyderabad, Andhra Pradesh, IN
3 Livestock Research Institute, College of Veterinary Science, Hyderabad, Andhra Pradesh, IN
4 Department of Animal Nutrition, College of Veterinary Science, Hyderabad, Andhra Pradesh, IN